Publication List

Research Articles

Preprints

  • Schulte, L., L. Uhrig, J. Eichberg, M. Schwartze, I. Auth, M. Schulz, T. Lindner, P. Hien, K. Hardes, A. Vilcinskas, T. Lüddecke (2024): Comparative venom analysis between melanistic and normally-coloured phenotypes of the common adder (Vipera berus). Biorxiv: 10.1101/2024.03.18.585504.
  • Dersch, L., A. Stahlhut, J. Eichberg, A. Paas, K. Hardes, A. Vilcinskas, T. Lüddecke (2024): Engineering a wolf spider A-family toxin towards increased antimicrobial activity but low toxicity. Biorxiv: 10.1101/2024.03.04.583312. 
  • Dresler, J., V. Herzig, A. Vilcinskas, T. Lüddecke (2024): Enlightening the toxinological dark matter of spider venom enzymes. Biorxiv: 10.1101/2024.02.27.582330.
  • Peng, J., T. Dederichs, T. Lüddecke, P. Michalek, A. Mucciolo, M. Robinson-Rechavi, G. Zancolli (2023): Beyond venomous fangs: Uloboridae spiders have lost their venom apparatus but not their toxins. Biorxiv:10.1101/2023.06.26.546488.


2024

  • Lüddecke, T., S. Blank (2024):  Animal Toxins: Biodiscovery, Mechanistic Insights and Translational Potential. Toxins 16(3), 130.

2023

  • Kaderka, R., T. Lüddecke, M. Rezac, V. Rezacova, M. Hüsser (2023):  Revision of the Peruvian tarantula Homoeomma peruvianum (Chamberlin, 1916): description of a new genus with eleven new species and insights to the evolution of montane tarantulas (Araneae: Theraphosidae: Theraphosinae). Journal of Natural History 57(41-44), 1710-1824.
  • Lüddecke, T., M. Damm, S. Laxme, C. Dawson (2023): Diversity, self-perception and future perspectives of early career researchers in toxinology: Lessons from the 21st world congress of the international society on toxinology. Toxicon 107343.
  • Schulte, S., M. Damm, I. Avella, L. Uhrig, P. Erkoc, S. Schiffmann, R. Fürst, T. Timm, G. Lochnit, A. Vilcinskas, T. Lüddecke (2023): Venomics of the Milos viper (Macrovipera schweizeri) unveils patterns of venom composition and exochemistry across blunt-nosed viper venom. Frontiers in Molecular Biosciences 10: 10.3389/fmolb.2023.1254058.
  • Dibiasi, W., T. Lüddecke (2023): First report of envenomation symptoms caused by the Eastern Montpellier snake, Malpolon insignitus (St.-Hilaire, 1827). Toxicon: 233, 107255.
  • Vocadlova, K., T. Lüddecke, M.A. Patras, M. Marner, C. Hartwig, K. Benes, V. Matha, P. Mraz, T.F. Schäberle, A. Vilcinskas (2023): Extracts of Talaromyces purpureogenus Strains from Apis mellifera Bee Bread Inhibit the Growth of Paenibacillus spp. In Vitro. Microorganisms 11: 2067.
  • Herzig, V., T. J. Hauke, T. Lüddecke (2023): Unmasking trends and drivers of the international arachnid trade. Frontiers in Arachnid Science 2:1161383.
  • Lüddecke, T. (2023): Quid Pro Quo: A Documented Case of Cannibalism in the Red-Bellied Black Snake Pseudechis porphyriacus in Lamington (Queensland, Australia). Diversity 15(5): 610.
  • Lüddecke, T., A. Paas, R.J. Harris, L. Talmann, K.N. Kirchhoff, A. Billion, K. Hardes, A. Steinbrink, D. Gerlach, B.G. Fry, A. Vilcinskas (2023): Venom biotechnology: casting light on natures deadliest innovations using synthetic biology. Frontiers in Bioengineering and Biotechnology 11:1166601.
  • Lüddecke, T., L. Dersch, L. Schulte, S. Hurka, A. Paas, M. Oberpaul, J. Eichberg, K. Hardes, S. Klimpel, A. Vilcinskas (2023): Functional profiling of the A-family of venom peptides from the Wolf spider Lycosa shansia. Toxins 15(5), 303.

2022

  • Hurka, S., T. Lüddecke, A. Paas, L. Dersch, L. Schulte, J. Eichberg, K. Hardes, K. Brinkrolf, A. Vilcinskas (2022): Bioactivity Profiling of In Silico Predicted Linear Toxins from the Ants Myrmica rubra and Myrmica ruginodis.Toxins 14(12), 846.
  • Erkoc, P., B.M. von Reumont, T. Lüddecke, M. Henke, T. Ulshöfer, A. Vilcinskas, R. Fürst, S. Schiffmann (2022): The Pharmacological Potential of Novel Melittin Variants from Honeybee and Solitary Bees in the Context of Inflammation and Cancer. Toxins 14(12), 818.
  • Eichberg, J., E. Maiworm, M. Oberpaul, V. Czudai-Matwich, T. Lüddecke, A. Vilcinskas, K. Hardes (2022): Antiviral Potential of Natural Resources against Influenza Infections. Viruses 14, 2452.
  • Von Reumont, B.M., G. Anderluh, A. Antunes, N. Ayvazyan, D. Beis, F. Caliskan, A. Crnkovic, M. Damm, S. Dutertre, L. Ellgaard, G. Gajski, H. German, B. Halassy, B.F. Hempel, T. Hucho, N. Igci, M.P. Ikonomopoulou, I. Karbat, M.I. Klapa, I. Koludarov, J. Kool, T. Lüddecke, R.B. Mansour, M.V. Modica, Y. Moran, A. Nalbantsoy, M.E. Pachon Ibanez, A. Panagiotopolous, E. Reuveny, J. Sanchez Cespedes, A. Sombke, J.M. Surm, E.A.B. Undheim, A. Verdes, G. Zancolli (2022): Modern venomics – Current insights, novel methods and future perspectives in biological and applied animal venom research. Gigascience 11, giac048.
  • Hurka, S., K. Brinkrolf, R. Özbek, F. Förster, A. Billion, J. Heep, T. Timm, G. Lochnit, A. Vilcinskas, T. Lüddecke (2022): Venomics of the Central European Myrmicine Ants Myrmica rubra and Myrmica ruginodis. Toxins 14(5): 358.
  • Lüddecke, T., V. Herzig, B. M. von Reumont, A. Vilcinskas (2022): The biology and evolution of spider venoms. Biological Reviews 97: 163-178.
  • Krämer, J., T. Lüddecke, M. Marner, E. Maiworm, J. Eichberg, K. Hardes, T. Schäberle, A. Vilcinskas, R. Predel (2022): Antimicrobial, Insecticidal and Cytotoxic Activity of Linear Venom Peptides from the Pseudoscorpion Chelifer cancroides. Toxins 14(1): 58.
  • Lüddecke, T. (2022): The venoms of insects – often overlooked chemical arsenals. Antenna 46(1): 19-24.
  • Lüddecke, T., A. Vilcinskas (2022): Heilen mit Tiergiften: Tödliche Waffen des Tierreichs zur Therapie von Krankheiten nutzbar machen. Chemie in unserer Zeit 56 (2), doi: 10.1002/ciuz.202100005.

2021

  • Lüddecke, T., A. Paas, L. Talmann, K.N. Kirchhoff, B.M. von Reumont, A. Billion, T. Timm, G. Lochnit, A. Vilcinskas (2021): A Spider Toxin Exemplifies the Promises and Pitfalls of Cell-free Protein Production for Venom Biodiscovery. Toxins 13: 575.
  • Kaderka, R., N. Ferretti, M. Hüsser, T. Lüddecke, R.C. West (2021): Antikuna, a new genus with seven new species from Peru (Araneae: Theraphosidae: Theraphosinae) and the highest altitude record for the family. Journal of Natural History 55(21-22): 1335-1402.
  • Schmidtberg, H., B.M. von Reumont, S. Lemke, A. Vilcinskas, T. Lüddecke (2021): Morphological Analysis Reveals a Compartmentalized Duct in the Venom Apparatus of the Wasp Spider (Argiope bruennichi). Toxins 13(4): 270.
  • Rancilhac, L., I. Irisarri, C. Angelini, J.W. Arntzen, W. Babik, F. Bossuyt, S. Künzel, T. Lüddecke, F. Pasmans, E. Sanchez, D. Weisrock, M. Veith, B. Wielstra, S. Steinfartz, M. Hofreiter, M. Vences (2021): Phylotranscriptomic evidence for pervasive ancient hybridisation among Old world salamanders. Molecular Phylogenetics and Evolution 155: 106967.

2020

  • Lüddecke, T., B.M. von Reumont (2020): Venomics: Tiergifte als Quelle neuartiger Bioressourcen. BIOspektrum 26(7): 724-727.
  • Jung, L., J. Dusek, T. Lüddecke, V. Schulz, K. Maier-Sam, L. Habich, A. Mosebach, M. Lierz, H.P. Ziemek (2020): Epidemiological screening of captive salamanders reveals current absence of Batrachochytrium salamandrivorans in private collections throughout the federal state of Hesse (Germany). Salamandra 56(3): 233-238.
  • Lüddecke, T. (2020): Recent advances in Salamandra skin poison research. Toxicon 177, Suppl1: 6.
  • Lüddecke, T., B.M. von Reumont, F. Förster, A. Billion, T. Timm, G. Lochnit, A. Vilcinskas, S. Lemke (2020): The venom gland transcriptome of the wasp spider Argiope bruennichi. Toxicon 177, Suppl1: 42-43.
  • Lüddecke, T. (2020): Translational tarantula phylogenomics: Evolution of theraphosid spiders and their defensive arsenal with implications for venom bioprospecting. Toxicon 177, Suppl1: 27.
  • von Reumont, B.M., T. Lüddecke, T. Timm, G. Lochnit, A. Vilcinskas, J. von Döhren, M. Nilsson (2020): Proteo-Transcriptomic Analysis Identifies Potential Novel Toxins Secreted by the Predatory, Prey-Piercing Ribbon Worm Amphiporus lactifloreus. Marine Drugs 18(8): 407.
  • Lüddecke, T., B.M. von Reumont, F. Förster, A. Billion, T. Timm, G. Lochnit, A. Vilcinskas, S. Lemke (2020): An Economic Dilemma Between Molecular Weapon Systems May Explain an Arachno-atypical Venom in Wasp Spiders (Argiope bruennichi). Biomolecules 10: 978.

2019

  • Lüddecke, T. (2019): Über das Hautgift beim Feuersalamander. Feldherpetologisches Magazin 11: 9-16.
  • Lüddecke, T., A. Vilcinskas, S. Lemke (2019): Phylogeny-Guided Selection of Priority Groups for Venom Bioprospecting: Harvesting Toxin Sequences in Tarantulas as a Case Study. Toxins 11: 488.
  • Foley, S., T. Lüddecke (shared first-authorship), D.Q. Cheng, H. Krehenwinkel, S. Künzel, S.J. Longhorn, I. Wendt, V. von Wirth, R. Tänzler, M. Vences, W.H. Piel (2019): Tarantula phylogenomics: A robust phylogeny of deep theraphosid clades inferred from transcriptome data sheds light on the prickly issue of urticating setae evolution. Molecular Phylogenetics and Evolution 140: 106573.
  • Stawikowski R., T. Lüddecke (2019): Description of defensive postures of the natterjack toad (Epidalea calamita) and notes on the release of toxic secretions. Herpetology Notes 12: 443-445.
  • Knepper, J., T. Lüddecke, K. Preißler, M. Vences, S. Schulz (2019): Isolation and Identification of Alkaloids from Poisons of Fire Salamanders (Salamandra salamandra). Journal of Natural Products 82(5).
  • Preißler, K., S. Gippner, T. Lüddecke, T.E. Krause, S. Schulz, M. Vences, S. Steinfartz (2019): More yellow more toxic? Sex rather than alkaloid content is correlated with yellow coloration in the fire salamander. Journal of Zoology doi:10.1111/jzo12676.
  • Sanchez, E., H. Pröhl, T. Lüddecke, S. Schulz, S. Steinfartz, M. Vences (2019): The conspicuous postmetamorphic coloration of fire salamanders, but not their toxicity, is affected by larval background albedo. Journal of Experimental Zoology B – Molecular and Developmental Evolution doi: 10.1002/jez.b.22845.

2018

  • Lüddecke, T., S. Schulz, S. Steinfartz, M. Vences (2018): A salamander’s toxic arsenal: review of skin poison diversity and function in true salamanders, genus Salamandra.  The Science of Nature 105: 56.
  • Lüddecke, T., H. Krehenwinkel, G. Canning, F. Glaw, S. Longhorn, R. Tänzler, I. Wendt, M. Vences (2018): Discovering the silk road: Nuclear and mitochondrial sequence data resolve the phylogenetic relationships among theraphosid spider subfamilies.  Molecular Phylogenetics and Evolution 119: 63-70.
  • Sanchez, E., E. Küpfer, D.J. Goedbloed, A.W. Nolte, T. Lüddecke, S. Schulz, M. Vences, S. Steinfartz (2018): Morphological and transcriptomic analyses reveal three discrete primary stages of postembryonic development in the common fire salamander, Salamandra salamandra. Journal of Experimental Zoology B – Molecular and Developmental Evolution 330: 96-108.

Book Chapters

2024

  • Lüddecke, T. (2024): Heilen statt Vergiften: Vergangenheit, Gegenwart und Zukunft von Tiergiften in der biomolekularen Wirkstoffforschung. In: Ach, J.S. Edt. (2024): Tiere in der Medizin. Mentis/Brill, in press.

Popular Science Articles

2023

  • Koester, V., T. Lüddecke (2023): Exploring the Untapped Power of Animal Venoms. ChemistryViews: 10.1002/chemv.202300042.
  • Lüddecke, T., A. Vilcinskas (2023): Healing with Venom – Part 2. ChemistryViews: 10.1002/chemv.202300008.
  • Lüddecke, T., A. Vilcinskas (2023): Healing with Venom – Part 1. ChemistryViews: 10.1002/chemv.202200112.

2022

  • Lüddecke, T. (2022): Unknown poisoners: Exploring spider venoms for novel biomolecules. Fraunhofer IME Annual Report 2021: 48-49.

2021

  • Reinhardt, N., T. Lüddecke (2021): Die Gattung Phoneutria im Fokus: Taxonomie, Toxikologie und Haltung. ARACHNE 26(4): 06-24.
  • Lüddecke, T. (2021): Spider venom as a source for novel bioresources. Fraunhofer IME Annual Report 2020: 35-36.

2020

  • Lüddecke, T. (2020): Das neue Gifttiergesetz in Nordrhein-Westfalen – Eine Übersicht. ARACHNE 25(4): 29-35.
  • Lüddecke, T. (2020): Stammesgeschichte der Vogelspinnen und die Evolution ihrer Verteidigungsstrategien, erklärt mit Phylogenomik. ARACHNE 25(3): 6-8.
  • Lüddecke, T. (2020): Nachruf auf Dr. Norman I. Platnick (1951-2020). ARACHNE 25(2): 6-8.

2018

  • Lüddecke, T. (2018): Sequenzdatenbasierte Einblicke in den Stammbaum der Theraphosidae und eine Einführung in die molekulare Phylogenetik. ARACHNE 23(4): 4-13.

Theses

2021

  • Lüddecke, T. (2021): How the integration of phylogenetics and venomics resolves persistent challenges in evolutionary systematics and toxinology – lessons from the spider kingdom. Doctoral Thesis, Justus Liebig University of Gießen (summa cum laude).

2018

  • Lüddecke, T. (2018): Biochemical analyses of salamander chemical defense: Characterization of novel toxins and survey of the Salamandra skin poison proteome. Master Thesis, Technical University of Braunschweig (1,0).

2016

  • Lüddecke, T. (2016): Analysen von Salamander-Alkaloiden durch Gaschromatographie: Methodenentwicklung, Metabolismus und Variabilität. Bachelor Thesis, Technical University of Braunschweig (1,0).

Oral Presentations

2024

  • Lüddecke, T. (2024): Spinnengifte für den biologischen Pflanzenschutz. 26. Jahrestagung of the AK biologischer Pflanzenschutz, German Society for Phytopathology (Gießen, Germany).
  • Lüddecke, T. (2024): Animal Venomics - wie die tödlichsten Waffen des Tierreichs zur Medizin von morgen werden. Invited talk at DGHT Regionalgruppe Saarland (Neunkirchen, Germany). 

2023

  • Lüddecke, T. (2023): A birds eye perspective on venom biotechnology. Invited talk at Interdisciplinary Summer School on Snakebite Envenoming of the Bernhard Nocht Institute for Tropical Medicine (Hamburg, Germany). 
  • Lüddecke, T. (2023): Animal Venomics. Invited talk at Deutscher Herpetologentag 2023 of DGHT (Neustadt an der Aisch/ Germany).
  • Lüddecke, T. (2023): Tierische Giftmischer: Über die natürliche Funktion von Tiergiften, hin zur menschlichen Nutzung. Invited talk to Jungchemiker Forum at University of Greifswald (Greifswald/ Germany).
  • Lüddecke, T. (2023): Turning toxic arsenals into life saving drugs: lessons from the venoms of small arthropods. Invited talk at PPGSBio Journey (Boa Vista/ Brazil, held online).
  • Lüddecke, T. (2023): Heilende Gifte: Wie die tödlichsten Waffen des Tierreichs zur Medizin von Morgen werden. Invited talk at Tiere in der Medizin (Greifswald/ Germany).

2022

  • Lüddecke, T. (2022): Harnessing novel bio resources from venoms of small arachnids. Invited talk at 21st World Congress of the International Society on Toxinology 2022 (Abu Dhabi/ United Arab Emirates).
  • Lüddecke, T. (2022): The chemical diversity in arachnid venom as a source for bimolecular innovation in medicine and agriculture". INSECTA 2022 Conference (Gießen/ Germany).
  • Lüddecke, T. (2022): Achtbeinige Pharmazeuten: Wie Spinnengift zu Medizin wird. Invited talk at Senckenberg Arachnolgisches Treffen 2022 (Frankfurt am Main/ Germany).
  • Lüddecke, T. (2022): Heilen statt Vergiften: Arthropodengifte als Quelle biomolekularer Innovation. Invited talk to the biological colloquium at Siegen University (Siegen, Germany).
  • Lüddecke, T. (2022): Arthropodengifte als Quelle neuer Bioressourcen. Invited talk to the department of molecular evolution and systematics of animals, university of Leipzig (Leipzig, Germany).

2021

  • Lüddecke, T. (2021): Heilen statt Vergiften: Wie Spinnengifte der Menschheit nutzen können. Invited talk to DeArGe seminar series (online).
  • Lüddecke, T. (2021): Biology of spider venoms: where are we and what is missing? Invited talk to the International Toxin Talks 2021 (online).
  • Lüddecke, T. (2021): Many-legged assassins and master chemists: understanding arthropod venoms as a source for biomolecular innovation. Keynote talk to the Ento21 conference of the Royal Entomological Society (online).

2019

  • Lüddecke, T. (2019): Neue Methoden an die Front! Wie genetische Informationen helfen die Evolution von Vogelspinnen und ihrer charakteristischen Merkmale aufzuklären. Invited talk to the 54. International Tarantula Fair (Marbach am Neckar/ Germany, 2019).
  • Lüddecke, T. (2019): Recent advances in Salamandra skin poison research. 20th World Congress of the International Society on Toxinology (Buenos Aires/ Argentina, 2019)
  • Lüddecke, T. (2019):Translational tarantula phylogenomics: Evolution of theraphosid spiders and their defensive arsenal with implications for venom bioprospecting. 20th World Congress of the International Society on Toxinology (Buenos Aires/ Argentina, 2019).
  • Lüddecke, T. (2019): On the Evolution of Theraphosidae: Phylogenomics of tarantulas unravels major genetic lineages and suggests a rapid diversification in the Americas. Invited talk to the 2nd Congresso Latinoamericano de Biogeografia & Humboldt 250 Conference of the International Biogeography Society (Quito/ Ecuador, 2019).
  • Lüddecke, T. (2019): Probenahme am Feuersalamander - Theorie und Praxis. Workshop Feuersalamander II - Desinfektion und Probenahme (Hofbieber/ Germany, 2019).
  • Lüddecke, T. (2019): Probenahme am Feuersalamander - Theorie und Praxis. Workshop Feuersalamander - Desinfektion und Probenahme (Wetzlar/ Germany, 2019).
  • Lüddecke, T. (2019): Genetic and phenotypic changes during metamorphosis and  determination of the developmental origin of toxicity in the common fire salamander (Salamandra salamandra). Net@Phys workshop in animal physiology (Rauischholzhausen/ Germany, 2019).

2018

  • Lüddecke, T. (2018): The past, present and future of Salamandra skin poison research. Invited talk to the Deutscher Herpetologentag of the DGHT (Magdeburg/ Germany, 2018).
  • Lüddecke, T. (2018): Stammbäume aus dem Reagenzglas: Neue Erkenntnisse und Methoden der Vogelspinnensystematik mittels Molekulargenetik. Invited talk to the Spring meeting of the ZAG Wirbellose e.V. (Halle/ Germany, 2018).
  • Lüddecke, T. (2018): Vogelspinnensystematik im molekularbiologischen Zeitalter. Invited talk to the Arachnoweekend of the DeArGe e.V. (Hessisch Lichtenau/ Germany, 2018).

Political Statements and Open Letters

2020

  • Meurer, A., T. Lüddecke (2020): Anfrage zum Sachstand im Gesetzgebungsverfahren zu einem Gefahrtiergesetz NRW (Drs 17/7367) und einem Gifttiergesetz NRW (Drs 17/8297). (2020)
  • Lüddecke, T., T.J. Hauke, V. Herzig (2020): Stellungnahme der Deutschen Arachnologischen Gesellschaft (DeArGe e.V.) zum Entwurf des  geplanten Gifttiergesetzes (GiftTierG) in Nordrhein-Westfalen. Stellungnahme 17/2432 (2020).